Xeroderma pigmentosum, or XP, is a genetic disorder of DNA repair in which the body's normal ability to remove damage caused by ultraviolet (UV) light is deficient. This leads to multiple basaliomas and other skin malignancies at a young age. In severe cases, it is necessary to avoid sunlight.

Some of the most common symptoms of XP are:

• An unusually severe sunburn after a short sun exposure. The sunburn may last for several weeks. The sunburn usually occurs during a child’s first sun exposure.
• Development of many freckles at an early age.
• Irregular dark spots on the skin.
• Thin skin.
• Excessive dryness of skin.
• Rough-surfaced growths (solar keratoses), and skin cancers.
• Eyes that are painfully sensitive to the sun and may easily become irritated, bloodshot, and clouded.
• Blistering or freckling on minimum sun exposure.
• Premature aging of skin, lips, eyes, mouth and tongue.

The Structure of the Human Centrin 2-Xeroderma Pigmentosum Group C ...
interactions between centrin and xeroderma pigmentosum group C ... Peptide Synthesis—The human xeroderma pigmentosa group C pep- ...

Xeroderma pigmentosa | Health Library | Walgreens
Xeroderma pigmentosa is an inherited inability of the skin to repair DNA damage from ... Xeroderma pigmentosa is inherited as an autosomal recessive trait. ...

Xeroderma pigmentosa
Xeroderma pigmentosa is an inherited inability of the skin to repair DNA damage from ... Xeroderma pigmentosa is inherited as an autosomal recessive trait. ...

Malignant melanoma of conjunctiva with xeroderma pigmentosa - a ...
Xeroderma Pigmentosa is a rare autosomal recessive disease. ... Presented here is a rare and unusual case of xeroderma pigmentosa with malignant melanoma of ...